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HST 162/163
Molecular Diagnostics and Bioinformatics

Term: Fall

Course Director(s): Georg K. Gerber, Long P. Le
Time:
T 2-5
Location:
TMEC - 328 (2nd half of term; starts 10/31)
Course Website:
None
Prerequisite:
HST.015 and HST.191 recommended.
Restrictions:
Only HST students may register under HST.162, P/D/F. Enrollment limited, preference to HST students.
MIT Units:
2-0-4 (G-Level Credit )
Harvard Units:
Unknown
Introduction of molecular diagnostic methods in medicine and relevant bioinformatics methods. Discussion of principles of molecular testing for diagnosis of somatic and germline diseases using FISH, classical genotyping, array CGH, next generation sequencing, and other technologies. Case conferences emphasize clinical correlation and integration of information from multiple diagnostic tests. Bioinformatics lectures, problem sets, and laboratory sessions will introduce key concepts in biological sequence analysis and provide experience with bioinformatics tools.