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HST 508
Evolutionary Genomics

Term: Fall

Course Director(s): Leonid A. Mirny, Tami Lieberman
Time:
M/W 11am-12:30pm
Location:
MIT: 56-154
Course Website:
None
Prerequisite:
Permission of instructor
Restrictions:
None
MIT Units:
3-0-9 (G-Level Credit)
Harvard Units:
4 (B)
Develops deep quantitative understanding of basic forces of evolution, molecular evolution, genetic variations and their dynamics in populations, genetics of complex phenotypes, and genome-wide association studies. Applies these foundational concepts to cutting-edge studies in epigenetics, gene regulation and chromatin; cancer genomics and microbiomes. Modules consist of lectures, journal club discussions of high-impact publications, and guest lectures that provide clinical correlates. Homework assignments and final projects develop practical experience and understanding of genomic data from evolutionary principles.