May 16, 2014
This Week in HST
Volume 15, Number 35

HST Community Notices


Course Information

Conferences, Lectures & Seminars

Student Opportunities

Professional Opportunities

Career Programs

HST Community Notices



VACU Scan - Video Amplification of Cutaneous Ulcers was the winner of the President’s Challenge, and receives an award of $70,000 to implement the concept. VACU Scan is a novel point-of-care service that accurately and affordably assesses local cutaneous perfusion by amplifying the near-invisible color changes in regular digital video captured by a mobile phone. This paradigm enables the observation and measurement of key diagnostic information in any setting and by any clinician. HMS students Ben Brush, Steve Xu, and Richard Lin (HST) are on the team, as well as an HST Honors recipient from last year, Khang Nguyen.

The Harvard Gazzette news article can be found here.

Congratulations all!



Emily Rosen has been awarded summer funding from the American Society of Hematology, and Daniel Haldar has been selected as the summer fellow for the St. Baldrick's award.

Congratulations Emily and Daniel!



Congratulations to MD Student Winston Yan on receiving a Paul & Daisy Soros Fellowship for New Americans!
Further info on the Soros Foundation may be found at



We are delighted to report that the following awards were presented at the HST Spring Dinner at the Harvard Club of Boston on April 30:
Irving M. London Teaching Award, honoring faculty who have made outstanding contributions to the training of HST students, was awarded to Dr. Thomas N. Byrne, clinical professor of Neurology and HST and director of the HST 312 Clinical Reasoning Through CPCs.
Thomas A. McMahon Mentoring Award, honoring faculty who inspire and nurture HST students in their scientific and personal growth through honest advice and generosity, was awarded to Dr. Konstantina Stankovic, assistant professor of otology and laryngology, HMS and HST MD and Speech and Hearing Sciences alumna.
Seidman Prize for MD Research Mentorship, honoring faculty for outstanding research mentorship of an HST MD student, was awarded to Dr. Bohdan Pomahac, associate professor of surgery, HMS.
Several Directors' Awards were presented for committee and teaching service:
Dr. Cecil H. "Pete" Coggins, associate professor of medicine, HMS
For service as chair of the interim HST Faculty Promotions Committee
Dr. Tayyaba Hasan, professor of dermatology and HST
For service as a member of the interim HST Faculty Promotions Committee
Dr. Frederick J. Schoen, professor of pathology and HST
For service as a member of the interim HST Faculty Promotions Committee
Dr. David E. Housman, Virginia and DK Ludwig Professor of Cancer Research and HST
Stepping down after 22 years of service as director of and lecturer in HST 160 Molecular Biology and Genetics in Modern Medicine
Dr. Anne B.S. Giersch, assistant professor of pathology, HMS
Stepping down after 7 years of service as co-director of and lecturer in HST 160 Molecular Biology and Genetics in Modern Medicine
Dr. Chinweike Ukomadu, assistant professor of Medicine, HMS
Stepping down as co-director of and lecturer in HST 120 Gastroenterology
Dr. Martin C. Carey, professor of medicine, HMS
Stepping down after 39 years as lecturer in and director of the HST 120 Gastroenterology course

Congratulations to all these remarkable, deserving honorees!

The National Academy of Sciences announced on April 29, 2014 the election of 84 new members and 21 foreign associates from 15 countries in recognition of their distinguished and continuing achievements in original research.
Congratulations are in order for Co-Director, HST MIT and Associate Director, IMES MIT, Emery N. Brown; Warren M. Zapol Professor of Anaesthesia, department of anesthesia and critical care, MGH and HST MD Alumnus, Vamsi K. Mootha; investigator, HHMI; and professor of systems of biology and medicine, MGH Department of Molecular Biology, HMS.
All the best to Emery and Vamsi!


The Richard A. Gillis Award for Excellence in Medical Education was established in 2012 in memory of Rick Gillis (1953-2011), Executive Director of Curriculum Programs, whose 27 years of contributions to the MD program at Harvard Medical School exemplify the standards of excellence and the work ethic he inspired in those who were privileged to know him and to work with him. The award is given to a member or members of the HMS staff for their outstanding contributions to the educational mission of the School. This award serves as a reminder of Rick’s legacy and the critical role of staff in facilitating, in the words of his hero, President John F. Kennedy, “the infinite potential of the human mind that can be realized through education … [and that] can be translated into benefit for everyone and greater strength for our Nation.”

The 2014 Richard A. Gillis Award for Excellence in Medical Education has been awarded to Patty Cunningham, HST Academic Programs Administrator.
The award will be presented at the Teaching Awards Celebration on Monday, May 5th, 5-7:30 PM, in the Walter Amphitheatre and TMEC Atrium.
We are proud and thrilled that you have been honored in this way…
Congratulations, Patty!
Posted in MIT News on April 23, 2014...
Seven MIT faculty members are among 204 leaders from academia, business, public affairs, the humanities and the arts elected to the American Academy of Arts and Sciences, the academy announced today.
One of the nation’s most prestigious honorary societies, the academy is also a leading center for independent policy research. Members contribute to academy publications, as well as studies of science and technology policy, energy and global security, social policy and American institutions, the humanities and culture, and education.
Those elected from MIT this year are:
  • Elazer Reuven Edelman, the Thomas D. and Virginia W. Cabot Professor of Health Sciences and Technology
  • Michael Greenstone, the 3M Professor of Environmental Economics
  • Keith Adam Nelson, a professor of chemistry
  • Paul A. Seidel, a professor of mathematics
  • Gigliola Staffilani, the Abby Rockefeller Mauzé Professor of Mathematics
  • Sherry Roxanne Turkle, the Abby Rockefeller Mauzé Professor of the Social Studies of Science and Technology
  • Robert Dirk van der Hilst, the Schlumberger Professor of Earth Sciences and head of the Department of Earth,  Atmospheric and Planetary Sciences
“It is a privilege to honor these men and women for their extraordinary individual accomplishments,” Don Randel, chair of the academy’s Board of Directors, said in a statement. “The knowledge and expertise of our members give the Academy a unique capacity — and responsibility — to provide practical policy solutions to the pressing challenges of the day. We look forward to engaging our new members in this work.”
The new class will be inducted at a ceremony held on Oct. 11 at the academy’s headquarters in Cambridge.
Since its founding in 1780, the academy has elected leading “thinkers and doers” from each generation, including George Washington and Benjamin Franklin in the 18th century, Daniel Webster and Ralph Waldo Emerson in the 19th century, and Albert Einstein and Winston Churchill in the 20th century. The current membership includes more than 250 Nobel laureates and more than 60 Pulitzer Prize winners.
Congratulations, Elazer!
Community service is an integral part of the missions of Harvard Medical School and Harvard School of Dental Medicine. In faithfulness to this commitment, the Dean’s Community Service Award was established in 1999 to recognize individuals whose dedication and commitment to community service have made a positive impact on the local, national, or international community.
A 2014 Student Award has been granted to current HST MD candidate L. Nicholas Gonzalez Castro, PhD (HST MEMP, 2012) for his work with Boston Health Care for the HomelessThe community organization for which he was nominated will receive a check for $1,000.
Recipient categories include: Lifetime Achievement, Faculty, Trainee, Student and Staff.  Awards will be presented at the Dean's Community Service Award Recognition Breakfast on Thursday, June 19, 2014 from 8:00 - 9:30am in the Benjamin Waterhouse Room, Gordon Hall of Medicine, 1st Floor, 25 Shattuck Street, Boston, MA.  
Since the inception of the Dean’s Community Service Award, Harvard Medical School has recognized the contributions of 92 individuals and donated $1,000 to 87 organizations that serve our community. Ten faculty members have been honored with a Lifetime Achievement Award for Community Service. 
Congratulations, Nick!
What is IDEA2?
IDEA2 is a program compromised of a multi-step process that turns an IDEA into IDEA2.
Why participate?
  • Learn to independently define and articulate a research idea.
  • Gain experience in developing a network of advisors from different disciplines, professions, and sectors.
  • Receive supplemental funding for your research. 
Who is eligible?
HST MD or PhD candidates: First, second, and third year students and/or any student who has not completed a thesis proposal. 
For more information and to apply, visit:
Deadline: Pre-proposals are due May 19, 2014



The “Martha Gray Prizes for Excellence in Research" were named to honor former MIT director Martha Gray.  Under Dr. Gray's leadership, HST's faculty, graduate programs and community outreach grew—underscoring her focus on developing connections among individuals.  Her passion for bringing together the diverse, yet interconnected, parts of the HST universe is part of her abiding legacy, and bears fruit in the breadth of HST student research. 

In the context of an impressive array of student research, the 2014 Martha Gray Prize Winners selected at the Forum were:

Bioinformatics and Integrative Genomics
Michael S. Rooney, “The Mutational Landscape of Immune-Infiltrated Tumors”    

Physiology and Systems Biology
Jared Mayers, “Elevated circulating branched chain amino acids are an early event in pancreatic adenocarcinoma development”

Imaging and Optics
Sheldon J.J. Kwok, “Multiphoton photoconvertible probe for in situ labeling of circulating cells”

Biomedical Devices
Andrew Warren, “Point-of-care diagnostics for cancer using synthetic urinary biomarkers and paper microfluidics”

Cell and Molecular Biology
Priya Srikanth, “Identifying critical functions of DISC1 disrupted in major mental illness”

Regenerative Medicine
Steven Castleberry, “Self-Assembled Wound Dressings Silence MMP-9 and Improve Diabetic Wound Healing In Vivo”

Congratulations to all Gray Prize winners!



Nikhil Vadhavkar has been awarded a NASA NSTRF Graduate Fellowship.
Congratulations, Nikhil!



Congratulations to Molly Plovanich who received the 2014 Seidman Prize for Outstanding HST Senior Medical Student Thesis! The Seidman Prize has been made possible by the generous donation of an endowment from an alumnus of the HST program, Dr. Kang Zhang, and is named in honor of Kricket and Jon Seidman, his graduate mentors.

Molly's thesis is titled: "Molecular Characterization of the Mitochondrial Calcium Uniporter." Molly will receive a plaque and a cash prize at HST Graduation on Friday, May 30, 3:00-6:00pm, MIT Media Lab.
Well done, Molly!

Lina Colucci (NSF GRFP)
David Miranda-Nieves  (NSF GRFP and NDSEG)
Varesh Prasad (NDSEG)

Congratulations, Lina, David, and Varesh!



We invite the IMES/HST community to visit the IMES Event Calendar for information on upcoming events. 

From the Web: 
Please use the following address to access the IMES Events Calendar in any web browser: 
To sync with an existing calendar:
Please use the following address to access the IMES Event calendar from other applications. You can copy and paste this into any calendar product that supports the iCal format:
Subscribe from an RSS feed reader:
Please use the following address to access your calendar from other applications. You can copy and paste this into any feed reader:



We cordially invite you to the 2013 HST Graduation celebration:

  • Friday, May 30, 2014
  • 3-6pm
  • MIT Media Lab, Building 14, 6th floor Reception Room
HST's graduation is a community celebration to recognize the accomplishments of the graduating class.
RSVP by going to and clicking on RVSP at the bottom of the menu column. Directions to the venue, parking information and the schedule may also be found at this website.
Questions may be sent to We look forward to seeing you there!



Congratulations to our HST MD award recipients. A number of students have received notification of awards for research and course work.  Please join us in acknowledging their accomplishment!
American Heart Association Award for 2014-15
(one year of funding for research)
David Wen Rui Wang
Howard Hughes Medical Institute Medical Research Fellows Program
(one year of funding for research)
Tru-Khang Dinh
Allison Hamilos
George Huang
Daniel Oh
Ryan Park
Avanthi Raghavan
Sarnoff Cardiovascular Research Foundation
(one year of funding for research)
Avanthi Raghavan
Howard Hughes Medical Institute Summer Medical Fellows Program
(summer funding for research)
Mai Dao
The Paul and Daisy Soros Fellowships for New Americans
Sana Raoof
David G. Nathan Summer Fellowship in Pediatric Hematology/Oncology
Brian Li
James Luccarelli
Sarvagna Patel

"If you don’t make mistakes, you’re not working on hard enough problems."
                    --FRANK WILCZEK
Or talking to the right people.
The HST REFS want to remind you that they are here for you if you are feeling stressed, frustrated, or simply want to talk to someone. The team is made up of five past and present HST students who are formally trained in mediation services, and can provide confidentiality and function independently of MIT. They are here to be your first point of contact for a range of issues including conflicts within lab or matters of a more personal nature. For more information about them, visit:
Any of the REFS are available for scheduled meetings at a mutually convenient time and location, so please feel free to email them at
Want to know how to find stuff at MIT and Harvard? 
For MIT, bookmark From academics to finances and community life to professional development, search and find the resources you need.
  • Search or browse for resources by topic or keyword
  • View undergraduate or graduate-specific resources
  • Short descriptions help you understand if a resource is what you are looking for
  • Mobile-friendly
For Harvard, the site is:

Course Information



KL2 Catalyst Medical Research Investigator Training (CMeRIT) Award
The KL2/CMeRIT program provides advanced training through educational activities and mentored research for senior fellows and junior faculty in C/T research. The award provides two years of salary support at 50-75% of the awardee’s institutional salary base within NIH guidelines. Please review the website for application instructions and detailed eligibility requirements.
Application closes May 29, 2014.
Responsible Conduct of Research (RCR Cambridge Area)
August 18, 20, & 22, 2014
This nine-hour course fulfills NSF & NIH requirements for formal RCR instruction for those desiring to deepen their knowledge of ethical research and responsible conduct. 
Application closes August 14, 2014.
Effectively Communicating Research
October 2-3, 2014
A two-day course designed to provide fellows and junior faculty with the skills necessary to express their science clearly to diverse audiences.
Application opens May 8, 2014
For more information please email
Mentored Clinical Research Experience
September 3-November 19, 2014
A twelve-week program designed to give basic science PhDs with little-to-no clinical research experience an immersion into the clinical research setting.
Application opens May 8, 2014.
For more information please email
Introduction to Translational Medicine
September 29-October 1, 2014 
This three-day survey course offers an introduction to the skills necessary to embark on a career in translational research.
Application opens May 16, 2014.
For more information please email
Leadership Strategies for the Researcher
October 16-17, 2014 
This course features interactive and didactic sessions, with a focus on leading/managing teams and navigating a career in research.
Application opens May 22, 2014.
For more information please email
Advanced Imaging: Imaging in Clinical/Translational Cardiovascular Research
September 16-18, 2014
A three-day course in advanced imaging modalities to help researchers utilize imaging technology in cardiovascular research.
Application opens May 22, 2014.
For more information please email
Introduction to Clinical Investigation
October 6-10, 2014
A five-day survey course that covers the T1-T4 clinical/translational research spectrum with a combination of lectures and workshops.
Application opens May 23, 2014.
For more information please email
Contact Us!
The Harvard Catalyst Education Program in C/T Science provides comprehensive opportunities for clinical & translational education including courses, online resources, mentored research, and masters programs.  To contact us with questions or to manage your subscription, please e-mail
Make the most of May with the MIT Libraries. No lines, no waiting, no clicks: automatic renewals from the  MIT Libraries and more. 
Introduction to Healthcare Delivery in the U.S.; Prereq: 15.060 and 15.761 or permission of instructor    
G (Fall), 9-units
Healthcare Lab: Introduction to Healthcare Delivery in the U.S. This new Action Learning Lab combines class sessions with senior leaders in healthcare and a 4-month long team project that delivers significant and concrete solutions to U.S.-based healthcare organizations.
H-Lab class sessions focus on:
The current business challenges and opportunities of the US healthcare delivery industry 
Providing a broad perspective of their effects on various career paths, such as consulting, entrepreneurship,
   hospital management, pharmaceutical, biomedical and IT innovation 
Providing students the opportunity to interact with outside speakers, including many top-level executives
Discussions based on practical examples from the ongoing healthcare related work of Sloan faculty,
   particularly, projects with local hospitals, such as MGH, Beth Israel Deaconess Medical Center (BIDMC),
   Children’s, and Brigham and Women’s Hospital

H-Lab project teams:
Work directly with a U.S.-based organization on an applied project 
Expect to meet regularly with your host organization and team during the semester 
Plan to spend time onsite at your host organization’s facility.
For more information about H-Lab contact
Course Team:
Retsef Levi, Professor and Team Mentor
Janet Wilkinson, Senior Lecturer and Team Mentor
Fall H1
Anjali Sastry
Interested in innovating amid constraints?
Learn what works, what doesn’t, and why, with our examination of ambitious startups and inspiring leading-edge organizations that are remaking healthcare delivery across the globe.
Entrepreneurs and leaders are pioneering new ways to scale up primary care, increase access to life-changing surgery, reduce maternal death, treat heart disease, and correct vision errors along with countless other needs. Far from the labs where new drugs and devices are developed, these innovators are developing novel business models that work on the front lines of care delivery. Some of the most promising innovations are emerging in resource-limited frontier markets.
We’ll look at these new approaches via cases, projects, and discussions with thought leaders, drawing on strategy, marketing, operations, systems thinking and other MBA tools and lenses. Join us if you’re interested in applying business thinking about scale, sustainability, and quality to one of the world’s most pressing problems: getting healthcare to the people who most need it.
Former students came up with five great reasons to take this class:
  • Fall H1-only (half semester, September to mid-October) class taught by a passionate MIT Sloan School of Management professor, Anjali Sastry, who draws on her experience in global health and System Dynamics
  • Not a class just for people interested in healthcare, but anyone interested in innovation and business models in low-resource settings.
  • If you have professional experience in front-line settings, learning what works and why will help to put in context everything you learned in tackling delivery challenges in the field.
  • A wonderful line-up of guest speakers, including case protagonists, experts in global health, business innovators, and thought leaders.
  • You get to choose a cutting-edge organization to analyze for the class, benefiting from expert guests' feedback on your take.
More about Business Model Innovation in Global Health
Across Africa, Latin America, and Asia, innovation in health care delivery is taking place in companies, non-profit enterprises, and at the private-public interface. Business Model Innovation: Global Health in Frontier Markets examines how new approaches to operations, revenue, marketing, finance, and strategy enable improved health care in resource-limited settings. Drawing on system dynamics, design thinking, and strategic analysis, we explore success and failure in innovative healthcare delivery. Our analysis of novel business models draws on case studies, videos, industry reports, research, and a compelling selection of expert guests. Students present their own assessments of innovative base-of-the-pyramid health enterprises that aim to do more with less.
MIT or cross-registered graduate students who have not taken at least three management or business classes must apply to the instructor ( for permission to enroll before the first day of class.



In the Summer 2014, the Teaching and Learning Lab will once again offer the Graduate Student Teaching Certificate Program.  This workshop series is for students interested in developing their teaching skills to support their teaching at MIT, as well as those who are planning careers in academe. To earn a certificate, students must participate in 7 classroom workshops, one online session, and a videotaped teaching/lesson presentation.
Registration is Required and space fills quickly!  Registration opens at 9:00 a.m. on Monday, April 14th here:
(Mark your calendars NOW! Space is limited and all sections are usually full 24-48 hours after registration opens).
The Summer Program is offered in an accelerated format. Class meetings will take place EVERY weekday from Tuesday: 5/27/14 thru Friday: 6/13/2014.   There will be 4 or 5 sections offered, with one dedicated to students in NON-science/engineering departments.  Summer program meeting dates are available here.
For any questions about the program, please contact Leann Dobranski (
The goals of this camp are to introduce you to programming in the MATLAB environment and to show you the power this provides for analyzing data and for gaining intuition about the behavior of complex systems through the use of numerical simulations. Some of you, upon encountering in the previous sentence words like "programming" and "numerical simulations," will feel the cold hand of fear grip your stomach, because you have never done any programming and, in fact, have tried to avoid math as much as possible. If so, YOU ARE PRECISELY THE PERSON WE HAD IN MIND as we were planning the course. We are aiming to help you break through this barrier of darkness and fear into the radiant sunshine of quantitative enlightenment. The true beauty of MATLAB, as we will personally demonstrate, is that it allows people who are not mathematically adept (e.g. some of the instructors of this course) to use powerful numerical methods and visualization tools to gain an understanding of concepts that are very difficult to grasp analytically.
While this course is geared for students with no previous programming experience, we will cover a range of topics that will be useful for people with stronger programming backgrounds.  Every exercise will have a range of components – including components that can be mastered by students with minimal programming, as well as advanced components for students with stronger backgrounds who want to dig a bit deeper. Furthermore, advanced students can explore MATLAB and quantitative approaches for analyzing biological problems through independent and TA-guided exercises.
To sign up: fill out the short survey at
Please fill this out even if you have already registered for the course or emailed about your interest in taking the course.
Dates: All the days will include plenty of break time and a longer lunch break.
  • Monday, 5/19: 9am - 5pm Matlab Intro Part 1
  • Tuesday, 5/20: 1pm - 5pm optional review
  • Wednesday, 5/21: 9am - 5pm Matlab Intro Part 2
  • Thursday, 5/22: 1pm - 5pm optional review
  • Friday, 5/23: 9am - 5pm Intro to Stats
  • Tuesday, 5/27: 9am - 5pm Intro to Image Analysis/Bioinformatics
  • Wednesday, 5/28: 9am - 5pm Special Topics (Bring your own data!)
Location: Maxwell Dworkin G115, Harvard Campus  
More course info: The first two days of the course will cover basics of programming intermixed with some image analysis and statistical methods for analyzing data.  The third day will focus on statistics; the fourth on image analysis/bioinformatics. The fifth day will focus on loading real data and 'solving' a problem that you bring from your own research.
The course assumes no knowledge of programming, statistics, bioinformatics, or image analysis.  The goal is to give people a set of practical tools that they can use towards any problem they want to address and to go through examples that both reinforces the different programming concepts and gives hands-on examples of data processing.
There are two optional days between the first and second day of the course and again between the second and third day of the course.  These optional sessions are aimed at the true novices to help give the extra practice and small group time often needed when learning something completely new.
If you desire, you can receive course credit for this boot camp, which is listed as Neurobiology 306qc.

Conferences, Lectures & Seminars



Consortium for Affordable Medical Technologies (CAMTech) at Massachusetts General Hospital (MGH) and the Institute for Medical Engineering and Science (IMES) at Massachusetts Institute of Technology (MIT) are joining together to offer Global Health focused medtech hackathons in both India and Uganda this summer.
The India hack-a-thon is July 18th – 20th (including travel July 14th through July 21) and Uganda hackathon is Aug 22nd – 24th (including travel August 19th through August 25th).
IMES will provide full travel funding for one student selected to attend each hack-a-thon.
The application deadline for IMES funding is May 23, and the application can be found here.  
(Please note that this is different from the deadlines and contact information found on the flyers advertising the hack-a-thons more generally.)

CAMTech India - Jugaad-a-thon

  • July 18-20, 2014
  • Bangalore, India

2nd CAMTech-MUST Hack-a-thon

  • August 22-24, 2014
  • Mbarara University of Science and Technology, Mbarara, Uganda
For more information, contact Robert Fadel (, Assistant Director for Administration, IMES at MIT
Flyers for the events can be seen here.

Life Science Trending Around the Globe-Making Local Innovations Go Global
  • Thursday, June 19, 2014
  • 5:30– 9pm
  • Merck Research Laboratories, 33 Avenue Louis Pasteur, Boston, MA 02115
Please join us for an amazing evening of science, innovation, and networking. Event registration is required with event sign-in beginning at 5:30 PM. Presentation and discussion will follow from 6:00 – 8:00 PM. Further, you are encouraged to bring your business cards, and enthusiasm, for an evening of networking following the presentation from 8:00-9:00 PM. Light food and refreshments will be provided during the networking portion of the evening.
Registration fee: $15.00
See event details and register at:



  • Tuesday May 20, 2014
  • 4–5pm
  • Ether Dome, Bulfinch Building, MGH
"Re-engineering the Tumor Microenvironment to Enhance Cancer Treatment: Bench to Bedside to Biomarkers"
Speaker: Rakesh Jain, A. Werk Cook Professor of Tumor Biology (Radiation Oncology), Director, Edwin L. Steele Laboratory for Tumor Biology, Massachusetts General Hospital and Harvard Medical School
Dr. Jain will discuss current research strategies and especially those of the future to understand the interactions of the extracellular matrix of tumors, cancer cells and stromal cells to increase the efficacy of diagnostic and therapeutic procedures.
Refreshments will be served.



Broken Hearts: The Tangled History of Cardiac Care
  • Wednesday, May 28, 2014
  • 5:30–6:30 pm 
  • Cannon Room/Building C/HMS Quad, Harvard Medical School, 240 Longwood Avenue, Boston, MA
Sponsored by The Boston Medical Library (
Speaker: David S. Jones, MD, PhD, A. Bernard Ackerman Professor of the Culture of Medicine, Faculty of Arts and Sciences and the Faculty of Medicine, Harvard University
Every day, all over America, people visit their doctors with chest pain and other symptoms of coronary artery disease.  Each year over a million of them choose to undergo bypass surgery or angioplasty.  Are these decisions good ones?  Even though modern medicine has committed itself to an ideal of evidence-based medicine, with its clinical trials, meta-analyses, and practice guidelines, the answer is not always clear.  By looking closely at the history of these procedures, it is possible to understand some of the reasons why this is the case.  One problem is that clinical trial data has never monopolized medical decisions.  Doctors and patients also pay attention to how treatments work, and if an intervention directly addresses the perceived cause of a disease -- as often happens with surgery -- then doctors assume that it will work.  The challenge here is figuring out whether or not our understanding of the causes of disease is correct.  The history of thinking about heart attacks shows how complicated this can be.  Another problem is that clinical research generally often under-estimates the risk of medical interventions. It is easier to study the desired outcomes of an intervention than its expected or unexpected complications.  As a result, doctors often end up with more thorough knowledge of a procedure’s efficacy than of its risks, an asymmetry that introduces a bias in favor of medical intervention.
The lecture is free of charge, but registration is required.
Contact: Roz Vogel, Countway Administration, (, 617-432-4807
The HMS JPNM offers a weekly seminar series from September through May.
Seminars are held on Thursdays at 8:00 am in the Fred S. Rosen Lecture Hall, HMS Quad 1st Floor, Modell Center, Armenise Building (
S. Ted Treves, MD, Program Director,
If you would like to be added to the weekly email distribution list for the lectures, please send an email to:
Jennifer Duane, JPNM Program Administrator,
Upcoming Seminars:
May 22, 2014
No Seminar - Clinical Nuclear Medicine and PET 2014 Course


Here is a link to the 2013/2014 Brainmap season.

Future topics will be similar to the previous Brainmap season, with some talks on Optogenetics, MR-PET, BOLD physiology, ultra-high field MRI, multimodal integration, contrast agents, and many more exciting topics!

Unless otherwise noted, seminars are held on Wednesdays at noon in seminar room CNY2204, MGH/Charlestown, Building 149.

To sign up for the mailing list, please go to:

May 21, 2014
Andre Bastos (MIT)
Visual areas exert feedforward and feedback influences through distinct frequency channels
May 28, 2014
Leah Somerville (Harvard)
Emotion, cognition, and the adolescent brain
June 4, 2014
Rudolph Pienaar (BCH)
TBA (Topic: web-based analysis software)
June 11, 2014
June 18, 2014
Juli Price (University of Pittsburgh)

Student Opportunities



START DATE: Summer/Fall 2014.
DESCRIPTION/OVERVIEW: We have one slot available for a full-time graduate research assistant fellow to work in the area of global health, funded by the TATA Center at MIT (  Our lab ( develops a variety of diagnostic tools based on low-cost sensors and mobile phone peripherals.  Technologies include impedance spectroscopy, electrochemical cells for gas detection, piezoelectric sensors for auscultation, and multi-spectral, thermal, and fluorescent imaging techniques implemented with a mobile phone.  Clinical applications include printed diagnostics, newborn assessment, maternal health, as well as screening and diagnostic tools for a variety of chronic or infectious diseases including pulmonary diseases (e.g. COPD, pneumonia, TB), anemia, and diabetes.  We are currently looking for an RA to work on real-time signal processing and lead the implementation of machine learning algorithms on the mobile phone.  The RA would collaborate with other people in the group currently developing the sensor electronics and low-level phone software.  Primary responsibilities include: Machine learning, statistical data analysis, software/algorithm development, coordinating with existing UROP students. Secondary responsibilities include: helping to deploy and test the technologies in the field (e.g. training and data collection) with our Indian clinical partners in various locations in India and other countries, publishing results in academic journals and conferences. Our lab collaborates locally with clinical researchers at Harvard School of Public Health, the Broad Institute, and Harvard Medical School. Faculty supervisor is Dr. Rich Fletcher (
Bachelor or Masters degree in Computer Science, Applied Mathematics, Physics, Electrical Engineering, Biomedical Engineering, or related field.
Strong interest in global health and willingness to spend time on-site (India).
Experience with statistical data analysis and machine learning techniques
Strong programming skills – particularly experience with developing software and algorithms for machine learning and statistical analysis.
Experience with Android development (JAVA or native C code) preferred
Must be self-motivated, resourceful, organized and able to work independently.
Good communication (verbal and written) and interpersonal skills a plus.
Two-year term (can apply for extension if needed).
ADDITIONAL REQUIREMENTS: Student must enroll and attend the Tata Pro-Seminar class, which meets once a week.  Fellowship recipients are also required to travel approximately 2 times per year to India; this generally consists of one short visit during IAP and a longer visit (4-6 weeks during the summer).
COMPENSATION: Fellowship includes full tuition for 2 years plus a monthly stipend year-round. Student can apply for an extension beyond 2 years (not guaranteed), if necessary.
CONTACT: Please send email Dr. Rich Fletcher ( describing your interest and include a resume or CV.  An informal interview will then be scheduled.


The L’Oréal For Women in Science program recognizes and rewards the contributions women make in the STEM fields and identifies exceptional women researchers committed to serving as role models for younger generations.  More than 2,000 women scientists in over 100 countries have been recognized since the program began in 1998. 
The L’Oréal USA For Women In Science fellowship program will award five post‐doctoral women scientists in the United States this year with grants of up to $60,000 each.
Applicants are welcome from a variety of fields, including the life and physical/material sciences, technology (including computer science), engineering, and mathematics.
Applications are available HERE and are due on Monday, May 19, 2014.
More information on the L’Oréal USA For Women in Science program can be found at
Should you have any questions or require additional information, please e‐mail
Thank you for considering this fellowship opportunity and for your help in advancing the role of women in science.

At the heart of the MIT mission statement is a call to serve the nation and the world—and this charge is embodied by the MIT Public Service Center. Every year, we send thousands of students into communities locally, across the nation, and around the globe to apply their skills and knowledge for the betterment of humankind. In the Institute's best traditions of hands-on experience, entrepreneurial spirit, and creative problem solving, these students donate their time, create new technologies, form communities and companies—and ultimately change lives everywhere they go.
As part of MIT's Division of Student Life, we provide a central point of communication and support for the outreach and humanitarian efforts of the MIT community. We engage students, alumni, staff, faculty, and others in life-changing initiatives and social entrepreneurship ventures that provide needed resources to individuals and communities.
The weekly Community Service Bulletin of Events and Programs can be found here.


Applications are now being accepted for funding by the Advanced Multimodal Neuroimaging Predoctoral Training Program.
The goal of this training program is to train future scientists in an interdisciplinary fashion, providing broad-based knowledge and skill sets that prepare them for career paths in neuroimaging research that crosses traditionally separate physical science and neuroscience domains.
Advanced graduate students enrolled in PhD programs at Harvard, HMS, and MIT, who have completed their qualifying exams, or the equivalent, are invited to apply. Accepted students will be appointed for a period of one year, and will carry out a neuroimaging research project co-mentored by the student's primary graduate advisor and a project co-mentor with complementary expertise. Additional information about the program - and about applying to the program - can be found on the Martinos Center website:
Interested students are asked to carefully read the guidelines for application and send the application form, along with an NIH biosketch, to Dr. Maria Mody (



The WHO Collaborating Centre for Surveillance of Antimicrobial Resistance is based at the Brigham and Women’s Hospital in Boston. In collaboration with the World Health Organization, we provide strategic and technical guidance to local and national infectious disease surveillance initiatives in over 90 countries.  A primary focus of our work is the development, dissemination, and support of the WHONET software for the management and analysis of microbiology laboratory data.  The software, available in 18 languages, is used by hospital, public health, veterinary, and food laboratories to study trends in antimicrobial resistance and bacterial infection.
Current Collaborations:
  • Local and national surveillance initiatives in over 90 countries
  • CDC MRSA Prevention Initiative
  • National Antimicrobial Resistance Monitoring System (NARMS)
  • European Antimicrobial Resistance Surveillance System (EARSS)
  • Models of Infectious Disease Agent Study (MIDAS)
Internship opportunities:  There are a number of areas where an intern or research assistant could contribute in important ways to our efforts:
  • Software development
  • Strategies for improving communication with and among users, including website development and electronic discussion forum
  • Research in automated outbreak detection and visualization
  • Support to U.S. and international WHONET users.  A current priority is hospitals in the CDC MRSA Prevention Initiative
For further information, please contact: John Stelling, Co-Director of the WHO Collaborating Centre for Surveillance of Antimicrobial Resistance, Brigham and Women’s Hospital, Boston, MA (



The Gerber Lab in the Center for Clinical and Translational Metagenomics at Brigham and Women’s Hospital/Harvard Medical School ( develops and applies novel computational and high-throughput experimental technologies to study mammalian microbiomes. The microbial inhabitants of the body form complex ecosystems that perform vital functions for the host. Alteration of the normal composition of the microbiota has been implicated as a contributing factor in a variety of human diseases, including susceptibility to infections, obesity, inflammatory bowel disease, allergies, multiple sclerosis, and cancer.

Particular areas of interest in the lab include developing novel machine learning methods for inferring dynamical behaviors of the microbiota, elucidation of microbe-microbe/host-microbe interaction networks, and prediction of disease status in patients from longitudinal microbiome and host immune system data; synthetic biology systems for discovering microbial factors important for effective gut colonization; and the role of the microbiota in protection against infectious and autoimmune diseases.
Interested students or post-docs should e-mail Dr. Georg Gerber (HST MEMP PhD ’07, MD ’09) at



Join a team working to develop a novel anti-reflex device based upon technology developed in the Draper lab at MIT!
We are seeking a candidate to aid in preclinical and clinical development in the Tavakkoli lab. The ideal candidate will have some background and comfort in at least one and ideally several of the following: mechanical engineering, chemical engineering, large animal models and clinical medicine. Motivated MD students looking for a project on a year of research, residents, post-docs and fellows are all welcome to apply.
Interest in entrepreneurship, GI, device development and learning about safety and tolerability criteria are all desirable. The position is financially supported for one year.  For more information, contact Dr. Jeffrey Ishizuka (

Professional Opportunities



Job Description

CytoVale is an early-stage startup bringing a mechanophenotyping approach to bear in diagnostics. The approach, developed at UCLA, exploits microfluidic phenomena and employs high-speed microscopic imaging to measure mechanical properties of cells (for more information on the technique, please see For the position of Scientific Programmer, we are seeking a dynamic individual with a lean startup mentality.
The applicant will be a computer scientist, biomedical engineer, or engineer in a related field with expertise in the areas of image processing, image analysis, controls systems, GUI development, and data analysis.
  • Software architecture planning and design for image analysis and machine learning
  • Developing the GUI for instrument control and data visualization
  • Optimizing the throughput of current analysis systems
  • Working closely and collaboratively with the engineering team
  • 2+ years of experience in aforementioned areas of work
  • Employ best coding practices
  • Proficiency in programming languages: C#, C/C++
  • Proficiency in scripting languages: MATLAB, Python
  • Desire to work in a high velocity startup
  • Experience with machine learning algorithms – logistic regression, SVM, k clustering, etc.
  • The ability to learn quickly and work independently
  • Hands on experience in a biology wet lab
Please send resumes to and reference the Scientific Programmer job listing.

CytoVale was co-founded by two HST Alums, Mara Macdonald and Ajay Shah.



Essential Function:

One of the leading investment groups in the world is seeking a Director of Informatics to create a human-AI hybrid system (e.g. freestyle chess) for prediction of group behavior, financial markets, and innovation trends. Experience required in visualization, data integration, machine learning, and hiring/management of a development team. This initiative will require continuous system development in response to evolving hardware and data sources, as well as commissioning proprietary hardware when software compromises are impossible or unreasonable. This project is a high priority within the firm and will be supported as such.

Technical & Behavioral Skills:
  • Exceptional technical skills in multiple technologies including:
  • HTML / CSS / JQuery
  • Working with databases § Version control (GIT)
  • MVC architecture
  • Unix environment
  • Grails
  • ASP.Net
  • PHP
  • Java
  • Ruby on Rails 
  • Python
  • The ability to fully design and implement an application using technology which supports concurrent users.
  • Experience with the full software development lifecycle, including planning, implementation, testing, and deployment.
  • Knowledge of coding best practices, including standards, documentation, scalability, and security.
  • Possess a fundamental understanding of user experience best practices.
  • A love of technology and a drive to constantly look for new ways to innovate and improve products and processes using new tools, frameworks, and creativity.
  • Demonstrates an intellectual curiosity and drive to stay up to date with the latest and greatest technologies.
  • Possesses a “can do” attitude and operates with a willingness to work hard and deliver high quality.
  • Ability to question software requirements and suggest different solutions if needed (not just follow instructions).
  • Shows conviction of belief while maintaining an open-minded nature and humility toward learning.
  • Flexible and able to manage ambiguity and complex problem solving.
  • Excellent interpersonal communication and teamwork skills.
  • Ability to work independently, both under supervision and as a contributing team member.
  • Ability to clearly and concisely articulate ideas and opinions.
  • Bachelor’s degree in Computer Science or equivalent (an advanced degree is a plus) 

Minimum work experience:

  • 5+ years experience in professional software development
  • Experience in smaller, entrepreneurial companies with a focus on results a plus

For inquiries, please contact:

Stephanie Moore at:
RA Capital Management, LLC | 20 Park Plaza, Suite 1200 | Boston, MA 02116


Computational Research Assistant
There is a computational research assistant position available in the laboratory of Prof. Martha Bulyk. The lab is located in the Division of Genetics at Brigham & Women’s Hospital, part of the Harvard Medical School research community in Boston, MA. 
Transcription factors regulate gene expression through DNA regulatory elements located in the noncoding portions of the genome. Discovery of the sequence features of DNA regulatory elements is essential for understanding how gene regulation is encoded in genomes. We are looking for an enthusiastic individual to perform research in computational genomics, including analysis of high-throughput experimental genomics data, development of new algorithms, programming efficient code, and benchmarking comparisons of software, for studies of transcriptional gene regulation in animal genomes.
B.S. and/or M.S. in Computer Science, Bioinformatics, or related field is required. Applicants with a bachelor’s degree in another area of concentration may be considered if the applicant has had significant coursework in the sciences and has the required skills and prior work experience. Strong background in mathematics, statistics, molecular biology, and DNA sequence analysis are required. Background and coursework in genomics and gene regulation are preferred. Prior experience working with Drosophila and/or mammalian genome sequences is strongly preferred. Must be proficient in Linux/Unix, Perl, C/C++, Java, and bash scripting.  Prior experience in Python, R or MATLAB is preferred. Must have prior experience in the software engineering life-cycle: data modeling, process modeling, prototyping, testing, release and maintenance, including change management, version control and release processes (familiarity with CVS and related tools). Must possess good analytical and organizational skills, strong troubleshooting and creative problem-solving skills, and the ability to work in a team setting on collaborative projects. At least 1 year of work experience and a flexible work schedule are required.  Fluent command of spoken and written English is absolutely required. 
This position offers a stimulating academic environment, opportunities to collaborate with biologists in a team setting, opportunities to gain valuable written and oral communication skills, and the possibility for co-authorship on publications. This position provides an excellent opportunity to be involved in cutting-edge research in genomics and to learn about experimental biology, while working on computational projects. Salary negotiable based upon work experience.
To apply for this position, please email a cover letter, CV, and contact information for 3 references to: (Please be sure to indicate whether visa sponsorship would be required).


Precisis US, Inc. is the new Boston based subsidiary of the German based medical device company and is looking for a research oriented Biomedical Engineer. This opportunity is located in the Cambridge area. 

Guided by an international team of renowned neuroscientists, develop a novel neuro stimulator to treat epilepsy. 
Design architecture and testing methods to ensure system design and component capability.
Perform full scope of electronic design, development and support efforts from design, layout, fabrication of both research and product based architectures.
Interface with mechanical and software engineers to ensure system meets specifications.
Organize and prioritize development efforts to ensure product schedules are maintained.
Evaluate electrical systems and components with respect to suitability for implantation in the human body. This will require hands on participation in all aspects of the electronics engineering process including design, implementation, verification and validation under clinical conditions.
Develop and execute best practices in medical device engineering. Responsible for creating and maintaining documentation of the design control process in accordance with FDA and ISO guidelines.
Coordinate with physician investigators for clinical testing of product.
Contribute to overall team success by accommodating and accomplishing related activities as needed.
Master’s or PhD, preferably in Biomedical Engineering
Experience in the electronics-based medical device industry
Ability to work with minimal supervision and to supervise a team
If Interested Please Contact:
Wolfgang Daum, PhD, President and CEO, Precisis US, Inc. (


NIH funded postdoctoral position available in the laboratory of Dr. Elliot L. Chaikof, MD, PhD, Johnson and Johnson Professor of Surgery, Harvard Medical School (, the Wyss Institute of Biologically Inspired Engineering at Harvard University (, and the Harvard Stem Cell Institute.
Project areas include:
Organ fabrication and tissue engineering. This project will involve the design, synthesis, assembly, and integration of artificial collagen and elastin fiber networks for the engineering of living tissues. Micro-fabrication techniques will be applied to dictate structure and resulting macro-scale properties. Applications are focused on cardiovascular and musculoskeletal tissues.  Studies will be directed at the development of strategies to promote tissue regeneration, delivery and differentiation of progenitor cells along appropriate lineage pathways, as well as designs to incorporate microvascular systems within engineered tissues. Available projects are appropriate for students with background or interests in molecular and cell biology, biomedical, mechanical and/or chemical engineering, as well as micro-fabrication, biomechanics, and the design of animal experiments (Biomaterials 2010; 27: 7175-7182; Advanced Materials 2010; 22:2041-2044; Biomaterials 2010;31:779-91; Advanced Drug Delivery Reviews 2010; 62: 1468-1478; Biomaterials 2011; 32: 5371-5379; Acta Biomaterialia 2012; 8: 627-635; Biomaterials 2012; 33:2431-8; Acta Biomaterialia 2012; 8: 988-997; Kumar VA, et al. In press Acta Biomaterialia 2013).
A Ph.D. in Biomedical Engineering or a related field is required. Submit CV and three references to or
Project description

Working independently and under general supervision from the Principal Investigator, the analyst will perform quantitative analyses for an NIH-funded study that uses unexpected death after medical encounters to study quality of care. The project is fundamentally multidisciplinary, integrating insights and methods from medicine, biostatisics, epidemiology, computer science, economics, and health policy. Work is based in the Department of Emergency Medicine at the Brigham & Women’s Hospital and Harvard Medical School, in collaboration with Ariadne Labs (Gawande), the department of Biostatistics at the Harvard School of Public Health (Dominici), the Harvard Economics Department, and the National Bureau of Economic Research (Cutler). The analyst will be responsible for performing statistical analyses, from basic parametric models to more innovative methods, using Medicare claims and clinical administrative data. There will be scope for the analyst to participate in the design and writing of individual manuscripts as an author, by mutual agreement.
BS or BA in statistics, engineering, computer science, economics, computational biology, or a related field. Advanced degrees are helpful but not required; pay is commensurate with experience.  
Demonstrated competency in Stata, R, or equivalent environments is required. Please submit a sample of code with your application.
To apply
Letter of interest, CV, and code sample to, or apply here.
The SoE dean's office will once again run an advertisement to help graduating PhDs and completing postdocs gain visibility, especially on the academic job market. The ad will run in First Bell, a content-aggregation newsletter produced by ASEE that has 27,000 recipients, 87% of whom are engineering faculty members at other universities. The ad will point to this site:
Any PhDs or postdocs who would like to be featured on the site should visit: and complete the form.

Career Programs



Contact Singapore, together with some of Singapore's leading medical and research institutes, invite you to join them at their networking and recruitment sessions in the East Coast to find out more about the clinical-science landscape and career opportunities available in Singapore.
  • Monday, May 19, 2014
  • 7–9pm (registration starts at 6.30pm)
  • Hotel Commonwealth, The Esplanade Room - 500 Commonwealth Avenue, Boston, MA 02215
They are looking for physician scientists, academic physicians and researchers in the following therapeutic areas of interest:
  • Cancer
  • Cardiovascular Diseases
  • Computational & Systems Biology
  • Dermatology
  • Health Services Research
  • Infectious Diseases/ Immunology
  • Metabolic Disorders
  • Neuroscience
  • Paediatrics
  • Pathology
  • Radiological Sciences
  • Stem Cell Biology
  • Stroke, Neuro-degenerative Diseases and Neuro-oncology

Are you a current graduate student (MBA, MPH, JD, Eng, Ph.D., MD etc), post doctoral fellow, or medical resident, interested in learning about the variety of career paths that exist within the life sciences sector?   Then stay tuned for our upcoming FILS series. Over the next year, we will provide insight about career paths in areas such as Life Sciences Consulting, Venture Capital, Business Development, Marketing, Product Management, Research and Development, Clinical Regulatory, Medical Affairs, Bioinformatics, Systems Biology,Modeling, Pharmacoeconomics, Reimbursement, Market Access, Patient Advocacy, Finance, Operations, Corporate Law and Patent Law.
Dates for the 2014 Series  are below and the full schedule is also on our website:
The FILS events are held at the MassBio offices at 300 Technology Square, 8th Floor, Cambridge MA from 5:30-8:00pm.  Together, Propel Careers, MassBio, and MassBioEd are committed to fostering the next generation of industry leaders in the life sciences.   
Tuesday, September 16, 2014
Bio-Informatics, Modeling and Systems Biology Career Paths
To register, visit:
Tuesday, October 21, 2014
Commercialization 2 (Reimbursement, Pharmacoeconomics, Patient Advocacy, and Market Access) Career Paths
To register, visit:
Tuesday, November 18, 2014
Finance, Legal, Operations Career Paths
To register, visit:



For those who are looking for other resources, recordings of career related workshops and sessions for grad students available here:

The GECD Event calendar can be found here:



Global Education & Career Development (GECD) is pleased to announce MIT’s subscription to The Versatile PhD, a web-based resource for PhDs considering careers beyond academia. Our subscription, generously supported by ODGE, can be accessed by students and alumni via GECD’s webpage and student CareerBridge accounts. Once students register, they can simply log in to the site directly (



There are hundreds of jobs and internships now posted on CareerBridge, under both the Job Search and the On-Campus Interviews tabs. Check both tabs and apply as soon as possible.



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