Fast Fact:
HST faculty member and pioneering biomedical engineer Robert Langer has been awarded the National Medal of Science.
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Degrees
- BS, Physical Sciences, Bangalore University, Bangalore, India, 1985
- MS, Biophysics, Harvard University, Cambridge, MA, 1987
- PhD, Medical Sciences, Harvard Medical School, Boston, MA, 1992
Selected Awards/Societies
- CaPCure Foundation, CaPCure Award, 1998-2001
- Beckman Foundation Young Investigator Award, 1999
- Burroughs Wellcome Fund Young Investigator Award in Pharamacological Sciences, 1999
- Edgerly Science Partnership Award, 1998
Research Interests
The Sasisekharan Laboratory employs multidisciplinary strategies to develop and integrate technologies to further study complex polysaccharides that are important to a host of disease processes. A central goal is to develop novel therapeutic approaches to alleviate suffering from disease and promote overall human health.
The vast structural complexity of glycans complicate the development of novel pharmacological approaches to treat human disease. In order to fully appreciate the therapeutic potential of glycan-based strategies, we are developing bioinformatics tools that will organize, integrate, and characterize the enormous amounts of data generated on glycan structure and function. Another thrust of the work is geared towards the development and extension of a variety of technological platforms that could advance our understanding of human health and disease. Prof. Sasisekharan participates in this field by coupling engineering and computational approaches to elucidate complex biomedical phenomena.
Reference Publications
- Raman R, Venkataraman M, Ramakrishnan S, Lang W, Raguram S, Sasisekharan R. Advancing Glycomics: Implementation Strategies at the Consortium for Functional Glycomics. Glycobiology. 2006 Feb 14
- Sengupta S, Eavarone D, Capila I, Zhao G, Watson N, Kiziltepe T, Sasisekharan R. Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system. Nature. 2005 Jul 28;436(7050):568-72
- Sasisekharan R, and Myette J (2003) The Sweet Science of Glycobiology American Scientist, September-October Issue
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