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HST 450
Biological Physics

Designed to provide seniors and first-year graduate students with a quantitative, analytical understanding of selected biological phenomena. Topics include experimental and theoretical basis for the phase boundaries and equation of state of concentrated protein solutions, with application to diseases such as sickle cell anemia and cataract. Protein-ligand binding and linkage and the theory of allosteric regulation of protein function, with application to proteins as stores as transporters in respiration, enzymes in metabolic pathways, membrane receptors, regulators of gene expression, and self-assembling scaffolds. The physics of locomotion and chemoreception in bacteria and the biophysics of vision, including the theory of transparency of the eye, molecular basis of photo reception, and the detection of light as a signal-to-noise discrimination.

Not Offered: Spring 2019

Instructor: G. Benedek