Spotlight

MEMP Alumni Profile: Fighting Cancer and Disease, One Lymph Node at a Time

Timothy P. Padera, MEMP PhD, ‘03, Associate Professor of Radiation Oncology at Massachusetts General Hospital/Harvard Medical School

Tim Padera works to fight cancer and disease by focusing his research on a far-reaching system of the body—the lymphatic system. As part of the Edwin L. Steele Laboratories for Tumor Biology at Massachusetts General Hospital, the Padera Laboratory uses novel intravital microscopy tools to examine how the lymphatic system drives the progression of cancer through metastatic spread as well as impairment in anti-tumor immune function. In addition, the Padera Lab studies the molecular control of lymphatic pumping and how pumping regulates antigen transport and the initiation of an immune response. These processes are dysfunctional in a variety of disease states including lymphedema and bacterial infections.

Although Padera’s research program is based in the lab, his clinical experiences as an HST MEMP student helped him define what is needed to have an impact on patient care. Patient care is ultimately what drives the work of the Padera Lab.

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