Courses

IMPORTANT NOTES

HST Preclinical Subjects (HST.011-HST.200)*:
Students not enrolled in an HST program are limited to two HST preclinical courses and must provide justification for enrolling in these courses. This action must be approved by the course director and the student’s advisor.

These subjects are scheduled according to the Harvard Medical School academic calendar, which differs from the MIT calendar. Students whose graduation depends upon completing one or more of these subjects should take particular care regarding the schedule.

*HST.163 & HST.198 are not included in the two-course limit.

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Fall 2025 -- IAP/Winter 2026 -- Spring 2026 -- Summer 2025

IAP/Winter 2026 and Spring 2026 schedules will be published in December 2025, links below go to descriptions only (see the additional links on this page for HST preclinical course schedule pdfs from HST@HMS)

Fall 2025

HT 007 GPS Growth of the Physician Scientist (restricted to 1st year MD students, registration through HMS only, August-June)
HST.010/HST.011 Human Functional Anatomy
HST.022 Integrations & Innovation in Medical Sciences I (restricted to 1st year MD students)
HST.030/HST.031 Human Pathology
HST.040/HST.041 Microbial Pathogenesis
HST.070/HST.071 Human Reproductive Biology
HST.120/HST.121 Gastroenterology
HST.130/HST.131 Neuroscience
HST.146/HST.147 Biochemistry and Metabolism
HST.150/HST.151 Principles of Pharmacology (previously offered during IAP/Spring)
HST.160/HST.161 Genetics in Modern Medicine
HST.162/HST.163 Molecular Diagnostics and Bioinformatics
HST.175/HST.176 Cellular and Molecular Immunology
HST.194/HST.195 Clinical Epidemiology (previously offered during IAP/Spring)
HST.196 Teaching Health Sciences and Technology
HST.198 Independent Study in Health Sciences and Technology
HST.202 Introduction to Clinical Medicine and Medical Engineering II (eligible students will be notified about registration)
HST.240 Translational Medicine Preceptorship
HST.452 Statistical Physics in Biology
HST.504 Topics in Computational Molecular Biology
HST.507J Advanced Computational Biology: Genomes, Networks, Evolution
HST.508 Evolutionary and Quantitative Genomics
HST.518J Human Systems Engineering
[HST.522J Biomaterials: Tissue Interactions - not offered regularly]
[HST.523J Cell-Matrix Mechanics - not offered regularly]
[HST.525J Tumor Microenvironment and Immuno-Oncology: A Systems Biology Approach - not offered Fall 2025]
HST.535J Tissue Engineering and Organ Regeneration
HST.540J Human Physiology
HST.542J Quantitative and Clinical Physiology
HST.560J Radiation Biophysics
[HST.565 Medical Imaging Sciences and Applications - not offered regularly]
[HST.580J Data Acquisition and Image Reconstruction in MRI - not offered Fall 2025]
[HST.583J Functional Magnetic Resonance Imaging: Data Acquisition and Analysis - not offered Fall 2025]
HST.590 Biomedical Engineering Seminar Series (Fall 2025 Topic: Healthcare Systems)
HST.599 Research in Health Sciences and Technology
[HST.716J Signal Processing by the Auditory System: Perception - not offered regularly]
HST.920J Principles and Practice of Drug Development
[HST.953 Collaborative Data Science in Medicine - not offered Fall 2025]
HST.974 Innovating for Mission Impact in Medicine and Healthcare
HST.999 Practical Experience in Health Sciences and Technology
HST.THG Graduate Thesis
HST.UR Undergraduate Research in Health Sciences and Technology
HST.URG Undergraduate Research in Health Sciences and Technology

IAP/Winter 2026

HST.018/019 Artificial Intelligence in Health Care II
HST.166/167 Principles of Biomedical Imaging II [NEW Course Offering. Restricted to HST students]
HST.200 Introduction to Clinical Medicine (course begins in the Spring term for AY26)
HST.202 Introduction to Clinical Medicine and Medical Engineering II (eligible students will be notified about registration)
HST.207 Introduction to Clinical Medicine and Medical Engineering* (continues in spring)
HST.434 Evolution of an Epidemic - IAP/Winter 2026 course website and application
HST.980 Emerging Problems in Infectious Diseases

Spring 2026

HST.020/HST.021 Musculoskeletal Pathophysiology*
HT 024 Integrations & Innovation in Medical Sciences II (restricted to 1st year MD students, registration through HMS only)
HST.034/HST.035 Pathology of Human Disease - please register for this course under HBTM 200 (Harvard), the MIT listing is being removed.
HST.060/HST.061 Endocrinology*
HST.080/HST.081 Hematology*
HST.090/HST.091 Cardiovascular Pathophysiology*
HST.100/HST.101 Respiratory Pathophysiology*
HST.110/HST.111 Renal Pathophysiology*
HST.196 Teaching Health Sciences and Technology
HST.198 Independent Study in Health Sciences and Technology
HST.200 Introduction to Clinical Medicine* (course begins in Spring term for AY26)
HST.202 Introduction to Clinical Medicine and Medical Engineering II (eligible students will be notified about registration)
HST.207 Introduction to Clinical Medicine and Medical Engineering* (eligible students will be notified about registration. Begins in IAP/Winter)
HST.220 Introduction to the Care of Patients* (restricted to MD students only - students must attend one pre-assigned virtual session in January)
HST.240 Translational Medicine Preceptorship
[HST.431J Infections and Inequalities: Interdisciplinary Perspectives on Global Health - not offered regularly]
[HST.438J | HST.439J Viruses, Pandemics, and Immunity - CANCELLED]
[HST.450J Biological Physics - not offered regularly]
HST.460J Statistics for Neuroscience Research
[HST.482J Biomedical Signal and Image Processing - not offered Spring 2026]
HST.500 Frontiers in (Bio)Medical Engineering and Physics
HST.506J Computational Systems Biology: Deep Learning in the Life Sciences
HST.515J Aerospace Biomedical and Life Support Engineering
HST.524J Design of Medical Devices and Implants - [course syllabus]
[HST.526J Future Medicine: Drug Delivery, Therapeutics, and Diagnostics - not offered regularly]
HST.531 Medical Physics of Proton Radiation Therapy
[HST.533 Medical Imaging in Radiation Therapy - not offered Spring 2026]
[HST.537J Fluids and Diseases - not offered Spring 2026]
HST.538J Genomics and Evolution of Infectious Disease
[HST.539J Frontiers of Interdisciplinary Science in Human Health and Disease - not offered Spring 2026]
[HST.541J Cellular Neurophysiology and Computing - not offered Spring 2026]
[HST.542J Quantitative and Clinical Physiology - not offered Spring 2026]
HST.552J Medical Device Design
HST.562J Pioneering Technologies for Interrogating Complex Biological Systems
[HST.563 Imaging Biophysics and Clinical Applications - not offered regularly]
[HST.576J Topics in Neural Signal Processing - not offered Spring 2026]
[HST.582J Biomedical Signal and Image Processing - not offered Spring 2026]
[HST.584J Magnetic Resonance Analytic, Biochemical, and Imaging Techniques - not offered Spring 2026]
HST.590 Biomedical Engineering Seminar Series (Spring 2026 topic: TBD)
HST.599 Research in Health Sciences and Technology
HT 700 Psychopathology and Introduction to Clinical Psychiatry (restricted to MD students, registration through HMS only)
HST.723J Audition: Neural Mechanisms, Perception and Cognition
[HST.728J Automatic Speech Recognition - not offered Spring 2026]
[HST.916J Case Studies and Strategies in Drug Discovery and Development - not offered regularly]
HST.918J Economics of Health Care Industries
HST.936/HST.937/HST.938 Global Health Informatics to Improve Quality of Care
[HST.940J Bioinformatics: Principles, Methods and Applications - not offered regularly]
HST.956J Machine Learning for Healthcare
HST.962 Medical Product Development and Translational Biomedical Research - 2^nd half of term (Course Site via MITx). Registered students must also "enroll" on the MITx site to access course materials and lectures.
HST.971J Strategic Decision Making in the Life Sciences
[HST.972J Medicine for Managers and Entrepreneurs Proseminar - not offered regularly]
HST.974 Innovating for Mission Impact in Medicine and Healthcare (restricted to MIT Catalyst Fellows)
HST.978J Healthcare Ventures
HST.999 Practical Experience in Health Sciences and Technology
HST.THG Graduate Thesis
HST.UR Undergraduate Research in Health Sciences and Technology
HST.URG Undergraduate Research in Health Sciences and Technology

Summer 2025